Report from the fourth international consensus meeting to harmonize core outcome measures for atopic eczema/dermatitis clinical trials (HOME initiative).
Identifieur interne : 001814 ( Main/Exploration ); précédent : 001813; suivant : 001815Report from the fourth international consensus meeting to harmonize core outcome measures for atopic eczema/dermatitis clinical trials (HOME initiative).
Auteurs : J R Chalmers [Royaume-Uni] ; E. Simpson [États-Unis] ; C J Apfelbacher [Allemagne] ; K S Thomas [Royaume-Uni] ; L. Von Kobyletzki [Suède] ; J. Schmitt [Allemagne] ; J A Singh [États-Unis] ; Svensson [Suède] ; H C Williams [Royaume-Uni] ; K. Abuabara [États-Unis] ; V. Aoki [Brésil] ; M. Ardeleanu [États-Unis] ; M. Awici-Rasmussen [Norvège] ; S. Barbarot [France] ; T L Berents [Norvège] ; J. Block [États-Unis] ; A. Bragg [Royaume-Uni] ; T. Burton ; K K Bjerring Clemmensen [Danemark] ; A. Creswell-Melville [Canada] ; M. Dinesen [Danemark] ; A. Drucker [Canada] ; L. Eckert [France] ; C. Flohr [Royaume-Uni] ; M. Garg [Danemark] ; L A A. Gerbens [Pays-Bas] ; A L B. Graff [Royaume-Uni] ; J. Hanifin [États-Unis] ; D. Heinl [Allemagne] ; R. Humphreys [Royaume-Uni] ; H A Ishii [Brésil] ; Y. Kataoka [Japon] ; Y A Leshem [États-Unis] ; B. Marquort ; M-A Massuel [France] ; S. Merhand [France] ; H. Mizutani [Japon] ; H. Murota [Japon] ; D F Murrell [Australie] ; T. Nakahara [Japon] ; I. Nasr ; K. Nograles [États-Unis] ; Y. Ohya [Japon] ; I. Osterloh [Royaume-Uni] ; J. Pander [Pays-Bas] ; C. Prinsen [Pays-Bas] ; L. Purkins [Royaume-Uni] ; M. Ridd [Royaume-Uni] ; T. Sach [Royaume-Uni] ; M-L A. Schuttelaar [Pays-Bas] ; S. Shindo [Japon] ; J. Smirnova [Suède] ; A. Sulzer [France] ; E. Synn Ve Gjerde [Norvège] ; R. Takaoka [Brésil] ; H. Vestby Talmo [France] ; M. Tauber [France] ; F. Torchet [Japon] ; A. Volke [Estonie] ; C-F Wahlgren [Suède] ; S. Weidinger [Allemagne] ; E. Weisshaar [Allemagne] ; A. Wollenberg [Allemagne] ; K. Yamaga [Japon] ; C Y Zhao [Australie] ; P I Spuls [Pays-Bas]Source :
- The British journal of dermatology [ 1365-2133 ] ; 2016.
Descripteurs français
- KwdFr :
- MESH :
English descriptors
- KwdEn :
- MESH :
- chemical , therapeutic use : Dermatologic Agents.
- therapy : Dermatitis, Atopic.
- Checklist, Clinical Trials as Topic, Global Health, Humans, Long-Term Care, Patient Reported Outcome Measures, Quality of Life, Review Literature as Topic, Treatment Outcome.
Abstract
This article is a report of the fourth meeting of the Harmonising Outcome Measures for Eczema (HOME) initiative held in Malmö, Sweden on 23-24 April 2015 (HOME IV). The aim of the meeting was to achieve consensus over the preferred outcome instruments for measuring patient-reported symptoms and quality of life for the HOME core outcome set for atopic eczema (AE). Following presentations, which included data from systematic reviews, consensus discussions were held in a mixture of whole group and small group discussions. Small groups were allocated a priori to ensure representation of different stakeholders and countries. Decisions were voted on using electronic keypads. For the patient-reported symptoms, the group agreed by vote that itch, sleep loss, dryness, redness/inflamed skin and irritated skin were all considered essential aspects of AE symptoms. Many instruments for capturing patient-reported symptoms were discussed [including the Patient-Oriented SCOring Atopic Dermatitis index, Patient-Oriented Eczema Measure (POEM), Self-Administered Eczema Area and Severity Index, Itch Severity Scale, Atopic Dermatitis Quickscore and the Nottingham Eczema Severity Score] and, by consensus, POEM was selected as the preferred instrument to measure patient-reported symptoms. Further work is needed to determine the reliability and measurement error of POEM. Further work is also required to establish the importance of pain/soreness and the importance of collecting information regarding the intensity of symptoms in addition to their frequency. Much of the discussion on quality of life concerned the Dermatology Life Quality Index and Quality of Life Index for Atopic Dermatitis; however, consensus on a preferred instrument for measuring this domain could not be reached. In summary, POEM is recommended as the HOME core outcome instrument for measuring AE symptoms.
DOI: 10.1111/bjd.14773
PubMed: 27436240
Affiliations:
- Allemagne, Australie, Brésil, Canada, Danemark, Estonie, France, Japon, Norvège, Pays-Bas, Royaume-Uni, Suède, États-Unis
- Alabama, Angleterre, Bade-Wurtemberg, Bavière, Californie, District de Dresde, District de Haute-Bavière, District de Karlsruhe, Grand Londres, Groningue (province), Hollande-Septentrionale, Hovedstaden, Kyūshū, Languedoc-Roussillon, Midi-Pyrénées, Nottinghamshire, Nouvelle-Galles du Sud, Occitanie (région administrative), Oregon, Pays de la Loire, Préfecture de Fukuoka, Région Bretagne, Région de Kantō, Saxe (Land), Schleswig-Holstein, Utrecht (province), État de New York, État de São Paulo, Île-de-France, Østlandet
- Amsterdam, Copenhague, Dresde, Fukuoka, Groningue, Heidelberg, Kiel, Londres, Montpellier, Munich, Nantes, Nottingham, Oslo, Paris, Redon, Sydney, São Paulo, Tokyo, Toulouse, Utrecht
- Université d'Amsterdam, Université de Kyūshū, Université de Nottingham
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Simpson</name><affiliation wicri:level="2"><nlm:affiliation>Department of Dermatology, Oregon Health and Science University, Portland, OR, U.S.A.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Dermatology, Oregon Health and Science University, Portland, OR</wicri:regionArea><placeName><region type="state">Oregon</region></placeName></affiliation></author><author><name sortKey="Apfelbacher, C J" sort="Apfelbacher, C J" uniqKey="Apfelbacher C" first="C J" last="Apfelbacher">C J Apfelbacher</name><affiliation wicri:level="1"><nlm:affiliation>Medical Sociology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Medical Sociology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg</wicri:regionArea><wicri:noRegion>Regensburg</wicri:noRegion><wicri:noRegion>Regensburg</wicri:noRegion><wicri:noRegion>Regensburg</wicri:noRegion></affiliation></author><author><name sortKey="Thomas, K S" sort="Thomas, K S" uniqKey="Thomas K" first="K S" last="Thomas">K S Thomas</name><affiliation wicri:level="4"><nlm:affiliation>Centre of Evidence Based Dermatology, University of Nottingham, Nottingham, U.K.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre of Evidence Based Dermatology, University of Nottingham, Nottingham</wicri:regionArea><orgName type="university">Université de Nottingham</orgName><placeName><settlement type="city">Nottingham</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Nottinghamshire</region></placeName></affiliation></author><author><name sortKey="Von Kobyletzki, L" sort="Von Kobyletzki, L" uniqKey="Von Kobyletzki L" first="L" last="Von Kobyletzki">L. Von Kobyletzki</name><affiliation wicri:level="1"><nlm:affiliation>Lund University, Skåne University Hospital, Department of Dermatology, Malmö, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Lund University, Skåne University Hospital, Department of Dermatology, Malmö</wicri:regionArea><wicri:noRegion>Malmö</wicri:noRegion></affiliation></author><author><name sortKey="Schmitt, J" sort="Schmitt, J" uniqKey="Schmitt J" first="J" last="Schmitt">J. Schmitt</name><affiliation wicri:level="3"><nlm:affiliation>Centre for Evidence-Based Healthcare, University of Dresden, Dresden, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Centre for Evidence-Based Healthcare, University of Dresden, Dresden</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Dresde</region><settlement type="city">Dresde</settlement></placeName></affiliation></author><author><name sortKey="Singh, J A" sort="Singh, J A" uniqKey="Singh J" first="J A" last="Singh">J A Singh</name><affiliation wicri:level="2"><nlm:affiliation>Medicine Service, Birmingham VA Medical Center, Birmingham, AL, U.S.A.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Medicine Service, Birmingham VA Medical Center, Birmingham, AL</wicri:regionArea><placeName><region type="state">Alabama</region></placeName></affiliation></author><author><name sortKey="Svensson, " sort="Svensson, " uniqKey="Svensson " first="" last="Svensson"> Svensson</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology and Venereology, Malmö University Hospital, Malmö, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Dermatology and Venereology, Malmö University Hospital, Malmö</wicri:regionArea><wicri:noRegion>Malmö</wicri:noRegion></affiliation></author><author><name sortKey="Williams, H C" sort="Williams, H C" uniqKey="Williams H" first="H C" last="Williams">H C Williams</name><affiliation wicri:level="4"><nlm:affiliation>Centre of Evidence Based Dermatology, University of Nottingham, Nottingham, U.K.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre of Evidence Based Dermatology, University of Nottingham, Nottingham</wicri:regionArea><orgName type="university">Université de Nottingham</orgName><placeName><settlement type="city">Nottingham</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Nottinghamshire</region></placeName></affiliation></author><author><name sortKey="Abuabara, K" sort="Abuabara, K" uniqKey="Abuabara K" first="K" last="Abuabara">K. Abuabara</name><affiliation wicri:level="2"><nlm:affiliation>Department of Dermatology, University of California San Francisco, San Francisco, California, CA, U.S.A.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Dermatology, University of California San Francisco, San Francisco, California, CA</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Aoki, V" sort="Aoki, V" uniqKey="Aoki V" first="V" last="Aoki">V. Aoki</name><affiliation wicri:level="3"><nlm:affiliation>Department of Dermatology, University of São Paulo Medical School, São Paulo, Brazil.</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Department of Dermatology, University of São Paulo Medical School, São Paulo</wicri:regionArea><placeName><settlement type="city">São Paulo</settlement><region type="state">État de São Paulo</region></placeName></affiliation></author><author><name sortKey="Ardeleanu, M" sort="Ardeleanu, M" uniqKey="Ardeleanu M" first="M" last="Ardeleanu">M. Ardeleanu</name><affiliation wicri:level="2"><nlm:affiliation>Immunology and Inflammation, Regeneron Pharmaceuticals, Inc., New York, NY, U.S.A.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Immunology and Inflammation, Regeneron Pharmaceuticals, Inc., New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Awici Rasmussen, M" sort="Awici Rasmussen, M" uniqKey="Awici Rasmussen M" first="M" last="Awici-Rasmussen">M. Awici-Rasmussen</name><affiliation wicri:level="3"><nlm:affiliation>Psoriasis and Eczema Association of Norway, Oslo, Norway.</nlm:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Psoriasis and Eczema Association of Norway, Oslo</wicri:regionArea><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation></author><author><name sortKey="Barbarot, S" sort="Barbarot, S" uniqKey="Barbarot S" first="S" last="Barbarot">S. Barbarot</name><affiliation wicri:level="3"><nlm:affiliation>Department of Dermatology, CHU de Nantes, Nantes, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Dermatology, CHU de Nantes, Nantes</wicri:regionArea><placeName><region type="region">Pays de la Loire</region><region type="old region">Pays de la Loire</region><settlement type="city">Nantes</settlement></placeName></affiliation></author><author><name sortKey="Berents, T L" sort="Berents, T L" uniqKey="Berents T" first="T L" last="Berents">T L Berents</name><affiliation wicri:level="3"><nlm:affiliation>Institute of Clinical Medicine, University of Oslo, Oslo, Norway.</nlm:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Institute of Clinical Medicine, University of Oslo, Oslo</wicri:regionArea><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation></author><author><name sortKey="Block, J" sort="Block, J" uniqKey="Block J" first="J" last="Block">J. Block</name><affiliation wicri:level="2"><nlm:affiliation>National Eczema Organisation, National Eczema Association, San Rafael, CA, U.S.A.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Eczema Organisation, National Eczema Association, San Rafael, CA</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Bragg, A" sort="Bragg, A" uniqKey="Bragg A" first="A" last="Bragg">A. Bragg</name><affiliation wicri:level="3"><nlm:affiliation>Chugai Pharma Europe Ltd., London, U.K.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Chugai Pharma Europe Ltd., London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Burton, T" sort="Burton, T" uniqKey="Burton T" first="T" last="Burton">T. Burton</name><affiliation><nlm:affiliation>No affiliation (patient representative U.K.).</nlm:affiliation><wicri:noCountry code="no comma">No affiliation (patient representative U.K.).</wicri:noCountry></affiliation></author><author><name sortKey="Bjerring Clemmensen, K K" sort="Bjerring Clemmensen, K K" uniqKey="Bjerring Clemmensen K" first="K K" last="Bjerring Clemmensen">K K Bjerring Clemmensen</name><affiliation wicri:level="3"><nlm:affiliation>Department of Dermatology, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Dermatology, Bispebjerg Hospital, University of Copenhagen, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Creswell Melville, A" sort="Creswell Melville, A" uniqKey="Creswell Melville A" first="A" last="Creswell-Melville">A. Creswell-Melville</name><affiliation wicri:level="1"><nlm:affiliation>Société Canadienne de l'Eczéma, Keswick, ON, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Société Canadienne de l'Eczéma, Keswick, ON</wicri:regionArea><wicri:noRegion>ON</wicri:noRegion></affiliation></author><author><name sortKey="Dinesen, M" sort="Dinesen, M" uniqKey="Dinesen M" first="M" last="Dinesen">M. Dinesen</name><affiliation wicri:level="1"><nlm:affiliation>LEO Pharma A/S, Industriparken 55, Ballerup, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>LEO Pharma A/S, Industriparken 55, Ballerup</wicri:regionArea><wicri:noRegion>Ballerup</wicri:noRegion></affiliation></author><author><name sortKey="Drucker, A" sort="Drucker, A" uniqKey="Drucker A" first="A" last="Drucker">A. Drucker</name><affiliation wicri:level="1"><nlm:affiliation>Division of Dermatology, University Health Network, Toronto, ON, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Division of Dermatology, University Health Network, Toronto, ON</wicri:regionArea><wicri:noRegion>ON</wicri:noRegion></affiliation></author><author><name sortKey="Eckert, L" sort="Eckert, L" uniqKey="Eckert L" first="L" last="Eckert">L. Eckert</name><affiliation wicri:level="1"><nlm:affiliation>Health Economics and Outcomes Research, Sanofi, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Health Economics and Outcomes Research, Sanofi</wicri:regionArea><wicri:noRegion>Sanofi</wicri:noRegion><wicri:noRegion>Sanofi</wicri:noRegion></affiliation></author><author><name sortKey="Flohr, C" sort="Flohr, C" uniqKey="Flohr C" first="C" last="Flohr">C. Flohr</name><affiliation wicri:level="3"><nlm:affiliation>St John's Institute of Dermatology, Guy's and St Thomas' Hospitals NHS Foundation Trust and King's College London, London, U.K.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>St John's Institute of Dermatology, Guy's and St Thomas' Hospitals NHS Foundation Trust and King's College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Garg, M" sort="Garg, M" uniqKey="Garg M" first="M" last="Garg">M. Garg</name><affiliation wicri:level="3"><nlm:affiliation>LEO Pharma, Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>LEO Pharma, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Gerbens, L A A" sort="Gerbens, L A A" uniqKey="Gerbens L" first="L A A" last="Gerbens">L A A. Gerbens</name><affiliation wicri:level="4"><nlm:affiliation>Department of Dermatology, Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Dermatology, Academic Medical Centre, University of Amsterdam, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region><settlement type="city">Amsterdam</settlement></placeName><orgName type="university">Université d'Amsterdam</orgName></affiliation></author><author><name sortKey="Graff, A L B" sort="Graff, A L B" uniqKey="Graff A" first="A L B" last="Graff">A L B. Graff</name><affiliation wicri:level="3"><nlm:affiliation>National Eczema Society, London, U.K.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>National Eczema Society, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Hanifin, J" sort="Hanifin, J" uniqKey="Hanifin J" first="J" last="Hanifin">J. Hanifin</name><affiliation wicri:level="2"><nlm:affiliation>Department of Dermatology, Oregon Health and Science University, Portland, OR, U.S.A.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Dermatology, Oregon Health and Science University, Portland, OR</wicri:regionArea><placeName><region type="state">Oregon</region></placeName></affiliation></author><author><name sortKey="Heinl, D" sort="Heinl, D" uniqKey="Heinl D" first="D" last="Heinl">D. Heinl</name><affiliation wicri:level="1"><nlm:affiliation>Medical Sociology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Medical Sociology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg</wicri:regionArea><wicri:noRegion>Regensburg</wicri:noRegion><wicri:noRegion>Regensburg</wicri:noRegion><wicri:noRegion>Regensburg</wicri:noRegion></affiliation></author><author><name sortKey="Humphreys, R" sort="Humphreys, R" uniqKey="Humphreys R" first="R" last="Humphreys">R. Humphreys</name><affiliation wicri:level="3"><nlm:affiliation>National Eczema Society, London, U.K.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>National Eczema Society, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Ishii, H A" sort="Ishii, H A" uniqKey="Ishii H" first="H A" last="Ishii">H A Ishii</name><affiliation wicri:level="3"><nlm:affiliation>Brazilian Atopic Dermatitis Association (AADA), São Paulo, Brazil.</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Brazilian Atopic Dermatitis Association (AADA), São Paulo</wicri:regionArea><placeName><settlement type="city">São Paulo</settlement><region type="state">État de São Paulo</region></placeName></affiliation></author><author><name sortKey="Kataoka, Y" sort="Kataoka, Y" uniqKey="Kataoka Y" first="Y" last="Kataoka">Y. Kataoka</name><affiliation wicri:level="1"><nlm:affiliation>Osaka Prefectural Medical Center for Respiratory and Allergic Disease, Osaka, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Osaka Prefectural Medical Center for Respiratory and Allergic Disease, Osaka</wicri:regionArea><wicri:noRegion>Osaka</wicri:noRegion></affiliation></author><author><name sortKey="Leshem, Y A" sort="Leshem, Y A" uniqKey="Leshem Y" first="Y A" last="Leshem">Y A Leshem</name><affiliation wicri:level="2"><nlm:affiliation>Department of Dermatology, Oregon Health and Science University, Portland, OR, U.S.A.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Dermatology, Oregon Health and Science University, Portland, OR</wicri:regionArea><placeName><region type="state">Oregon</region></placeName></affiliation></author><author><name sortKey="Marquort, B" sort="Marquort, B" uniqKey="Marquort B" first="B" last="Marquort">B. Marquort</name><affiliation><nlm:affiliation>No affiliation (patient representative Sweden).</nlm:affiliation><wicri:noCountry code="no comma">No affiliation (patient representative Sweden).</wicri:noCountry></affiliation></author><author><name sortKey="Massuel, M A" sort="Massuel, M A" uniqKey="Massuel M" first="M-A" last="Massuel">M-A Massuel</name><affiliation wicri:level="3"><nlm:affiliation>Sanofi-Aventis, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Sanofi-Aventis, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Merhand, S" sort="Merhand, S" uniqKey="Merhand S" first="S" last="Merhand">S. Merhand</name><affiliation wicri:level="3"><nlm:affiliation>Association Française de l'Eczéma, Redon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Association Française de l'Eczéma, Redon</wicri:regionArea><placeName><region type="region">Région Bretagne</region><region type="old region">Région Bretagne</region><settlement type="city">Redon</settlement></placeName></affiliation></author><author><name sortKey="Mizutani, H" sort="Mizutani, H" uniqKey="Mizutani H" first="H" last="Mizutani">H. Mizutani</name><affiliation wicri:level="1"><nlm:affiliation>Mie University, Graduate School of Medicine and Mie University Hospital Tsu, Mie, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Mie University, Graduate School of Medicine and Mie University Hospital Tsu, Mie</wicri:regionArea><wicri:noRegion>Mie</wicri:noRegion></affiliation></author><author><name sortKey="Murota, H" sort="Murota, H" uniqKey="Murota H" first="H" last="Murota">H. Murota</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology, Osaka University, Osaka, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Dermatology, Osaka University, Osaka</wicri:regionArea><wicri:noRegion>Osaka</wicri:noRegion></affiliation></author><author><name sortKey="Murrell, D F" sort="Murrell, D F" uniqKey="Murrell D" first="D F" last="Murrell">D F Murrell</name><affiliation wicri:level="3"><nlm:affiliation>Department of Dermatology, St George Hospital, Sydney, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Dermatology, St George Hospital, Sydney</wicri:regionArea><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region></placeName></affiliation></author><author><name sortKey="Nakahara, T" sort="Nakahara, T" uniqKey="Nakahara T" first="T" last="Nakahara">T. Nakahara</name><affiliation wicri:level="4"><nlm:affiliation>Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka</wicri:regionArea><orgName type="university">Université de Kyūshū</orgName><placeName><settlement type="city">Fukuoka</settlement><region type="province">Kyūshū</region><region type="prefecture">Préfecture de Fukuoka</region></placeName></affiliation></author><author><name sortKey="Nasr, I" sort="Nasr, I" uniqKey="Nasr I" first="I" last="Nasr">I. Nasr</name><affiliation><nlm:affiliation>Retired, no affiliation.</nlm:affiliation><wicri:noCountry code="subField">no affiliation</wicri:noCountry></affiliation></author><author><name sortKey="Nograles, K" sort="Nograles, K" uniqKey="Nograles K" first="K" last="Nograles">K. Nograles</name><affiliation wicri:level="2"><nlm:affiliation>Celgene Corporation, Greater New York City Area Pharmaceuticals, New York, NY, U.S.A.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Celgene Corporation, Greater New York City Area Pharmaceuticals, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Ohya, Y" sort="Ohya, Y" uniqKey="Ohya Y" first="Y" last="Ohya">Y. Ohya</name><affiliation wicri:level="3"><nlm:affiliation>Division of Allergy, Department of Medical Subspecialties, National Center for Child Health and Development, Tokyo, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Division of Allergy, Department of Medical Subspecialties, National Center for Child Health and Development, Tokyo</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region></placeName></affiliation></author><author><name sortKey="Osterloh, I" sort="Osterloh, I" uniqKey="Osterloh I" first="I" last="Osterloh">I. Osterloh</name><affiliation wicri:level="1"><nlm:affiliation>Ostermed Ltd., Kent, U.K.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Ostermed Ltd., Kent</wicri:regionArea><wicri:noRegion>Kent</wicri:noRegion></affiliation></author><author><name sortKey="Pander, J" sort="Pander, J" uniqKey="Pander J" first="J" last="Pander">J. Pander</name><affiliation wicri:level="3"><nlm:affiliation>Celgene BV, Utrecht, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Celgene BV, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation></author><author><name sortKey="Prinsen, C" sort="Prinsen, C" uniqKey="Prinsen C" first="C" last="Prinsen">C. Prinsen</name><affiliation wicri:level="3"><nlm:affiliation>Department of Epidemiology and Biostatistics, EMGO+ Institute for Health and Care Research, VU University Medical Centre, Amsterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Epidemiology and Biostatistics, EMGO+ Institute for Health and Care Research, VU University Medical Centre, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Purkins, L" sort="Purkins, L" uniqKey="Purkins L" first="L" last="Purkins">L. Purkins</name><affiliation wicri:level="1"><nlm:affiliation>Ziarco Pharma Ltd, Kent, U.K.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Ziarco Pharma Ltd, Kent</wicri:regionArea><wicri:noRegion>Kent</wicri:noRegion></affiliation></author><author><name sortKey="Ridd, M" sort="Ridd, M" uniqKey="Ridd M" first="M" last="Ridd">M. Ridd</name><affiliation wicri:level="1"><nlm:affiliation>School of Social & Community Medicine, University of Bristol, Bristol, U.K.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>School of Social & Community Medicine, University of Bristol, Bristol</wicri:regionArea><wicri:noRegion>Bristol</wicri:noRegion></affiliation></author><author><name sortKey="Sach, T" sort="Sach, T" uniqKey="Sach T" first="T" last="Sach">T. Sach</name><affiliation wicri:level="1"><nlm:affiliation>Health Economics Group, University of East Anglia, Norwich, U.K.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Health Economics Group, University of East Anglia, Norwich</wicri:regionArea><wicri:noRegion>Norwich</wicri:noRegion></affiliation></author><author><name sortKey="Schuttelaar, M L A" sort="Schuttelaar, M L A" uniqKey="Schuttelaar M" first="M-L A" last="Schuttelaar">M-L A. Schuttelaar</name><affiliation wicri:level="3"><nlm:affiliation>Department of Dermatology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Dermatology, University Medical Center Groningen, University of Groningen, Groningen</wicri:regionArea><placeName><settlement type="city">Groningue</settlement><region nuts="2" type="province">Groningue (province)</region></placeName></affiliation></author><author><name sortKey="Shindo, S" sort="Shindo, S" uniqKey="Shindo S" first="S" last="Shindo">S. Shindo</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology, Osaka University, Osaka, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Dermatology, Osaka University, Osaka</wicri:regionArea><wicri:noRegion>Osaka</wicri:noRegion></affiliation></author><author><name sortKey="Smirnova, J" sort="Smirnova, J" uniqKey="Smirnova J" first="J" last="Smirnova">J. Smirnova</name><affiliation wicri:level="1"><nlm:affiliation>Department of Public Health Sciences, Karlstad University, Karlstad, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Public Health Sciences, Karlstad University, Karlstad</wicri:regionArea><wicri:noRegion>Karlstad</wicri:noRegion></affiliation></author><author><name sortKey="Sulzer, A" sort="Sulzer, A" uniqKey="Sulzer A" first="A" last="Sulzer">A. Sulzer</name><affiliation wicri:level="3"><nlm:affiliation>Sanofi-Aventis, Montpellier, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Sanofi-Aventis, Montpellier</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Languedoc-Roussillon</region><settlement type="city">Montpellier</settlement></placeName></affiliation></author><author><name sortKey="Synn Ve Gjerde, E" sort="Synn Ve Gjerde, E" uniqKey="Synn Ve Gjerde E" first="E" last="Synn Ve Gjerde">E. Synn Ve Gjerde</name><affiliation wicri:level="3"><nlm:affiliation>Psoriasis and Eczema Association of Norway, Oslo, Norway.</nlm:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Psoriasis and Eczema Association of Norway, Oslo</wicri:regionArea><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation></author><author><name sortKey="Takaoka, R" sort="Takaoka, R" uniqKey="Takaoka R" first="R" last="Takaoka">R. Takaoka</name><affiliation wicri:level="3"><nlm:affiliation>Department of Dermatology, University of São Paulo Medical School, São Paulo, Brazil.</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Department of Dermatology, University of São Paulo Medical School, São Paulo</wicri:regionArea><placeName><settlement type="city">São Paulo</settlement><region type="state">État de São Paulo</region></placeName></affiliation></author><author><name sortKey="Vestby Talmo, H" sort="Vestby Talmo, H" uniqKey="Vestby Talmo H" first="H" last="Vestby Talmo">H. Vestby Talmo</name><affiliation wicri:level="3"><nlm:affiliation>Sanofi-Aventis, Montpellier, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Sanofi-Aventis, Montpellier</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Languedoc-Roussillon</region><settlement type="city">Montpellier</settlement></placeName></affiliation></author><author><name sortKey="Tauber, M" sort="Tauber, M" uniqKey="Tauber M" first="M" last="Tauber">M. Tauber</name><affiliation wicri:level="3"><nlm:affiliation>Toulouse University, Toulouse, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Toulouse University, Toulouse</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Midi-Pyrénées</region><settlement type="city">Toulouse</settlement></placeName></affiliation></author><author><name sortKey="Torchet, F" sort="Torchet, F" uniqKey="Torchet F" first="F" last="Torchet">F. Torchet</name><affiliation wicri:level="1"><nlm:affiliation>Mie University, Graduate School of Medicine and Mie University Hospital Tsu, Mie, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Mie University, Graduate School of Medicine and Mie University Hospital Tsu, Mie</wicri:regionArea><wicri:noRegion>Mie</wicri:noRegion></affiliation></author><author><name sortKey="Volke, A" sort="Volke, A" uniqKey="Volke A" first="A" last="Volke">A. Volke</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology, University of Tartu, Tartu, Estonia.</nlm:affiliation><country xml:lang="fr">Estonie</country><wicri:regionArea>Department of Dermatology, University of Tartu, Tartu</wicri:regionArea><wicri:noRegion>Tartu</wicri:noRegion></affiliation></author><author><name sortKey="Wahlgren, C F" sort="Wahlgren, C F" uniqKey="Wahlgren C" first="C-F" last="Wahlgren">C-F Wahlgren</name><affiliation wicri:level="1"><nlm:affiliation>Dermatology Unit, Department of Medicine, Karolinska Institutet, Solna, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Dermatology Unit, Department of Medicine, Karolinska Institutet, Solna</wicri:regionArea><wicri:noRegion>Solna</wicri:noRegion></affiliation></author><author><name sortKey="Weidinger, S" sort="Weidinger, S" uniqKey="Weidinger S" first="S" last="Weidinger">S. Weidinger</name><affiliation wicri:level="3"><nlm:affiliation>Department of Dermatology, Venereology and Allergy University Hospital Schleswig-Holstein, Kiel, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Dermatology, Venereology and Allergy University Hospital Schleswig-Holstein, Kiel</wicri:regionArea><placeName><region type="land" nuts="2">Schleswig-Holstein</region><settlement type="city">Kiel</settlement></placeName></affiliation></author><author><name sortKey="Weisshaar, E" sort="Weisshaar, E" uniqKey="Weisshaar E" first="E" last="Weisshaar">E. Weisshaar</name><affiliation wicri:level="3"><nlm:affiliation>Occupational and Environmental Dermatology, Department of Social Medicine, University of Heidelberg, Heidelberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Occupational and Environmental Dermatology, Department of Social Medicine, University of Heidelberg, Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Wollenberg, A" sort="Wollenberg, A" uniqKey="Wollenberg A" first="A" last="Wollenberg">A. Wollenberg</name><affiliation wicri:level="3"><nlm:affiliation>Department of Dermatology and Allergy, Ludwig-Maximilian University, Munich, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Dermatology and Allergy, Ludwig-Maximilian University, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName></affiliation></author><author><name sortKey="Yamaga, K" sort="Yamaga, K" uniqKey="Yamaga K" first="K" last="Yamaga">K. Yamaga</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology, Osaka University, Osaka, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Dermatology, Osaka University, Osaka</wicri:regionArea><wicri:noRegion>Osaka</wicri:noRegion></affiliation></author><author><name sortKey="Zhao, C Y" sort="Zhao, C Y" uniqKey="Zhao C" first="C Y" last="Zhao">C Y Zhao</name><affiliation wicri:level="3"><nlm:affiliation>Department of Dermatology, St George Hospital, Sydney, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Dermatology, St George Hospital, Sydney</wicri:regionArea><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region></placeName></affiliation></author><author><name sortKey="Spuls, P I" sort="Spuls, P I" uniqKey="Spuls P" first="P I" last="Spuls">P I Spuls</name><affiliation wicri:level="4"><nlm:affiliation>Department of Dermatology, Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Dermatology, Academic Medical Centre, University of Amsterdam, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region><settlement type="city">Amsterdam</settlement></placeName><orgName type="university">Université d'Amsterdam</orgName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2016">2016</date><idno type="RBID">pubmed:27436240</idno><idno type="pmid">27436240</idno><idno type="doi">10.1111/bjd.14773</idno><idno type="wicri:Area/PubMed/Corpus">001B72</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001B72</idno><idno type="wicri:Area/PubMed/Curation">001B48</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001B48</idno><idno type="wicri:Area/PubMed/Checkpoint">001B48</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001B48</idno><idno type="wicri:Area/Ncbi/Merge">003870</idno><idno type="wicri:Area/Ncbi/Curation">003870</idno><idno type="wicri:Area/Ncbi/Checkpoint">003870</idno><idno type="wicri:Area/Main/Merge">001809</idno><idno type="wicri:Area/Main/Curation">001814</idno><idno type="wicri:Area/Main/Exploration">001814</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Report from the fourth international consensus meeting to harmonize core outcome measures for atopic eczema/dermatitis clinical trials (HOME initiative).</title><author><name sortKey="Chalmers, J R" sort="Chalmers, J R" uniqKey="Chalmers J" first="J R" last="Chalmers">J R Chalmers</name><affiliation wicri:level="4"><nlm:affiliation>Centre of Evidence Based Dermatology, University of Nottingham, Nottingham, U.K.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre of Evidence Based Dermatology, University of Nottingham, Nottingham</wicri:regionArea><orgName type="university">Université de Nottingham</orgName><placeName><settlement type="city">Nottingham</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Nottinghamshire</region></placeName></affiliation></author><author><name sortKey="Simpson, E" sort="Simpson, E" uniqKey="Simpson E" first="E" last="Simpson">E. Simpson</name><affiliation wicri:level="2"><nlm:affiliation>Department of Dermatology, Oregon Health and Science University, Portland, OR, U.S.A.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Dermatology, Oregon Health and Science University, Portland, OR</wicri:regionArea><placeName><region type="state">Oregon</region></placeName></affiliation></author><author><name sortKey="Apfelbacher, C J" sort="Apfelbacher, C J" uniqKey="Apfelbacher C" first="C J" last="Apfelbacher">C J Apfelbacher</name><affiliation wicri:level="1"><nlm:affiliation>Medical Sociology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Medical Sociology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg</wicri:regionArea><wicri:noRegion>Regensburg</wicri:noRegion><wicri:noRegion>Regensburg</wicri:noRegion><wicri:noRegion>Regensburg</wicri:noRegion></affiliation></author><author><name sortKey="Thomas, K S" sort="Thomas, K S" uniqKey="Thomas K" first="K S" last="Thomas">K S Thomas</name><affiliation wicri:level="4"><nlm:affiliation>Centre of Evidence Based Dermatology, University of Nottingham, Nottingham, U.K.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre of Evidence Based Dermatology, University of Nottingham, Nottingham</wicri:regionArea><orgName type="university">Université de Nottingham</orgName><placeName><settlement type="city">Nottingham</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Nottinghamshire</region></placeName></affiliation></author><author><name sortKey="Von Kobyletzki, L" sort="Von Kobyletzki, L" uniqKey="Von Kobyletzki L" first="L" last="Von Kobyletzki">L. Von Kobyletzki</name><affiliation wicri:level="1"><nlm:affiliation>Lund University, Skåne University Hospital, Department of Dermatology, Malmö, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Lund University, Skåne University Hospital, Department of Dermatology, Malmö</wicri:regionArea><wicri:noRegion>Malmö</wicri:noRegion></affiliation></author><author><name sortKey="Schmitt, J" sort="Schmitt, J" uniqKey="Schmitt J" first="J" last="Schmitt">J. Schmitt</name><affiliation wicri:level="3"><nlm:affiliation>Centre for Evidence-Based Healthcare, University of Dresden, Dresden, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Centre for Evidence-Based Healthcare, University of Dresden, Dresden</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Dresde</region><settlement type="city">Dresde</settlement></placeName></affiliation></author><author><name sortKey="Singh, J A" sort="Singh, J A" uniqKey="Singh J" first="J A" last="Singh">J A Singh</name><affiliation wicri:level="2"><nlm:affiliation>Medicine Service, Birmingham VA Medical Center, Birmingham, AL, U.S.A.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Medicine Service, Birmingham VA Medical Center, Birmingham, AL</wicri:regionArea><placeName><region type="state">Alabama</region></placeName></affiliation></author><author><name sortKey="Svensson, " sort="Svensson, " uniqKey="Svensson " first="" last="Svensson"> Svensson</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology and Venereology, Malmö University Hospital, Malmö, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Dermatology and Venereology, Malmö University Hospital, Malmö</wicri:regionArea><wicri:noRegion>Malmö</wicri:noRegion></affiliation></author><author><name sortKey="Williams, H C" sort="Williams, H C" uniqKey="Williams H" first="H C" last="Williams">H C Williams</name><affiliation wicri:level="4"><nlm:affiliation>Centre of Evidence Based Dermatology, University of Nottingham, Nottingham, U.K.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre of Evidence Based Dermatology, University of Nottingham, Nottingham</wicri:regionArea><orgName type="university">Université de Nottingham</orgName><placeName><settlement type="city">Nottingham</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Nottinghamshire</region></placeName></affiliation></author><author><name sortKey="Abuabara, K" sort="Abuabara, K" uniqKey="Abuabara K" first="K" last="Abuabara">K. Abuabara</name><affiliation wicri:level="2"><nlm:affiliation>Department of Dermatology, University of California San Francisco, San Francisco, California, CA, U.S.A.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Dermatology, University of California San Francisco, San Francisco, California, CA</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Aoki, V" sort="Aoki, V" uniqKey="Aoki V" first="V" last="Aoki">V. Aoki</name><affiliation wicri:level="3"><nlm:affiliation>Department of Dermatology, University of São Paulo Medical School, São Paulo, Brazil.</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Department of Dermatology, University of São Paulo Medical School, São Paulo</wicri:regionArea><placeName><settlement type="city">São Paulo</settlement><region type="state">État de São Paulo</region></placeName></affiliation></author><author><name sortKey="Ardeleanu, M" sort="Ardeleanu, M" uniqKey="Ardeleanu M" first="M" last="Ardeleanu">M. Ardeleanu</name><affiliation wicri:level="2"><nlm:affiliation>Immunology and Inflammation, Regeneron Pharmaceuticals, Inc., New York, NY, U.S.A.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Immunology and Inflammation, Regeneron Pharmaceuticals, Inc., New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Awici Rasmussen, M" sort="Awici Rasmussen, M" uniqKey="Awici Rasmussen M" first="M" last="Awici-Rasmussen">M. Awici-Rasmussen</name><affiliation wicri:level="3"><nlm:affiliation>Psoriasis and Eczema Association of Norway, Oslo, Norway.</nlm:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Psoriasis and Eczema Association of Norway, Oslo</wicri:regionArea><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation></author><author><name sortKey="Barbarot, S" sort="Barbarot, S" uniqKey="Barbarot S" first="S" last="Barbarot">S. Barbarot</name><affiliation wicri:level="3"><nlm:affiliation>Department of Dermatology, CHU de Nantes, Nantes, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Dermatology, CHU de Nantes, Nantes</wicri:regionArea><placeName><region type="region">Pays de la Loire</region><region type="old region">Pays de la Loire</region><settlement type="city">Nantes</settlement></placeName></affiliation></author><author><name sortKey="Berents, T L" sort="Berents, T L" uniqKey="Berents T" first="T L" last="Berents">T L Berents</name><affiliation wicri:level="3"><nlm:affiliation>Institute of Clinical Medicine, University of Oslo, Oslo, Norway.</nlm:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Institute of Clinical Medicine, University of Oslo, Oslo</wicri:regionArea><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation></author><author><name sortKey="Block, J" sort="Block, J" uniqKey="Block J" first="J" last="Block">J. Block</name><affiliation wicri:level="2"><nlm:affiliation>National Eczema Organisation, National Eczema Association, San Rafael, CA, U.S.A.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Eczema Organisation, National Eczema Association, San Rafael, CA</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Bragg, A" sort="Bragg, A" uniqKey="Bragg A" first="A" last="Bragg">A. Bragg</name><affiliation wicri:level="3"><nlm:affiliation>Chugai Pharma Europe Ltd., London, U.K.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Chugai Pharma Europe Ltd., London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Burton, T" sort="Burton, T" uniqKey="Burton T" first="T" last="Burton">T. Burton</name><affiliation><nlm:affiliation>No affiliation (patient representative U.K.).</nlm:affiliation><wicri:noCountry code="no comma">No affiliation (patient representative U.K.).</wicri:noCountry></affiliation></author><author><name sortKey="Bjerring Clemmensen, K K" sort="Bjerring Clemmensen, K K" uniqKey="Bjerring Clemmensen K" first="K K" last="Bjerring Clemmensen">K K Bjerring Clemmensen</name><affiliation wicri:level="3"><nlm:affiliation>Department of Dermatology, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Dermatology, Bispebjerg Hospital, University of Copenhagen, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Creswell Melville, A" sort="Creswell Melville, A" uniqKey="Creswell Melville A" first="A" last="Creswell-Melville">A. Creswell-Melville</name><affiliation wicri:level="1"><nlm:affiliation>Société Canadienne de l'Eczéma, Keswick, ON, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Société Canadienne de l'Eczéma, Keswick, ON</wicri:regionArea><wicri:noRegion>ON</wicri:noRegion></affiliation></author><author><name sortKey="Dinesen, M" sort="Dinesen, M" uniqKey="Dinesen M" first="M" last="Dinesen">M. Dinesen</name><affiliation wicri:level="1"><nlm:affiliation>LEO Pharma A/S, Industriparken 55, Ballerup, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>LEO Pharma A/S, Industriparken 55, Ballerup</wicri:regionArea><wicri:noRegion>Ballerup</wicri:noRegion></affiliation></author><author><name sortKey="Drucker, A" sort="Drucker, A" uniqKey="Drucker A" first="A" last="Drucker">A. Drucker</name><affiliation wicri:level="1"><nlm:affiliation>Division of Dermatology, University Health Network, Toronto, ON, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Division of Dermatology, University Health Network, Toronto, ON</wicri:regionArea><wicri:noRegion>ON</wicri:noRegion></affiliation></author><author><name sortKey="Eckert, L" sort="Eckert, L" uniqKey="Eckert L" first="L" last="Eckert">L. Eckert</name><affiliation wicri:level="1"><nlm:affiliation>Health Economics and Outcomes Research, Sanofi, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Health Economics and Outcomes Research, Sanofi</wicri:regionArea><wicri:noRegion>Sanofi</wicri:noRegion><wicri:noRegion>Sanofi</wicri:noRegion></affiliation></author><author><name sortKey="Flohr, C" sort="Flohr, C" uniqKey="Flohr C" first="C" last="Flohr">C. Flohr</name><affiliation wicri:level="3"><nlm:affiliation>St John's Institute of Dermatology, Guy's and St Thomas' Hospitals NHS Foundation Trust and King's College London, London, U.K.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>St John's Institute of Dermatology, Guy's and St Thomas' Hospitals NHS Foundation Trust and King's College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Garg, M" sort="Garg, M" uniqKey="Garg M" first="M" last="Garg">M. Garg</name><affiliation wicri:level="3"><nlm:affiliation>LEO Pharma, Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>LEO Pharma, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Gerbens, L A A" sort="Gerbens, L A A" uniqKey="Gerbens L" first="L A A" last="Gerbens">L A A. Gerbens</name><affiliation wicri:level="4"><nlm:affiliation>Department of Dermatology, Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Dermatology, Academic Medical Centre, University of Amsterdam, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region><settlement type="city">Amsterdam</settlement></placeName><orgName type="university">Université d'Amsterdam</orgName></affiliation></author><author><name sortKey="Graff, A L B" sort="Graff, A L B" uniqKey="Graff A" first="A L B" last="Graff">A L B. Graff</name><affiliation wicri:level="3"><nlm:affiliation>National Eczema Society, London, U.K.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>National Eczema Society, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Hanifin, J" sort="Hanifin, J" uniqKey="Hanifin J" first="J" last="Hanifin">J. Hanifin</name><affiliation wicri:level="2"><nlm:affiliation>Department of Dermatology, Oregon Health and Science University, Portland, OR, U.S.A.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Dermatology, Oregon Health and Science University, Portland, OR</wicri:regionArea><placeName><region type="state">Oregon</region></placeName></affiliation></author><author><name sortKey="Heinl, D" sort="Heinl, D" uniqKey="Heinl D" first="D" last="Heinl">D. Heinl</name><affiliation wicri:level="1"><nlm:affiliation>Medical Sociology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Medical Sociology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg</wicri:regionArea><wicri:noRegion>Regensburg</wicri:noRegion><wicri:noRegion>Regensburg</wicri:noRegion><wicri:noRegion>Regensburg</wicri:noRegion></affiliation></author><author><name sortKey="Humphreys, R" sort="Humphreys, R" uniqKey="Humphreys R" first="R" last="Humphreys">R. Humphreys</name><affiliation wicri:level="3"><nlm:affiliation>National Eczema Society, London, U.K.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>National Eczema Society, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Ishii, H A" sort="Ishii, H A" uniqKey="Ishii H" first="H A" last="Ishii">H A Ishii</name><affiliation wicri:level="3"><nlm:affiliation>Brazilian Atopic Dermatitis Association (AADA), São Paulo, Brazil.</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Brazilian Atopic Dermatitis Association (AADA), São Paulo</wicri:regionArea><placeName><settlement type="city">São Paulo</settlement><region type="state">État de São Paulo</region></placeName></affiliation></author><author><name sortKey="Kataoka, Y" sort="Kataoka, Y" uniqKey="Kataoka Y" first="Y" last="Kataoka">Y. Kataoka</name><affiliation wicri:level="1"><nlm:affiliation>Osaka Prefectural Medical Center for Respiratory and Allergic Disease, Osaka, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Osaka Prefectural Medical Center for Respiratory and Allergic Disease, Osaka</wicri:regionArea><wicri:noRegion>Osaka</wicri:noRegion></affiliation></author><author><name sortKey="Leshem, Y A" sort="Leshem, Y A" uniqKey="Leshem Y" first="Y A" last="Leshem">Y A Leshem</name><affiliation wicri:level="2"><nlm:affiliation>Department of Dermatology, Oregon Health and Science University, Portland, OR, U.S.A.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Dermatology, Oregon Health and Science University, Portland, OR</wicri:regionArea><placeName><region type="state">Oregon</region></placeName></affiliation></author><author><name sortKey="Marquort, B" sort="Marquort, B" uniqKey="Marquort B" first="B" last="Marquort">B. Marquort</name><affiliation><nlm:affiliation>No affiliation (patient representative Sweden).</nlm:affiliation><wicri:noCountry code="no comma">No affiliation (patient representative Sweden).</wicri:noCountry></affiliation></author><author><name sortKey="Massuel, M A" sort="Massuel, M A" uniqKey="Massuel M" first="M-A" last="Massuel">M-A Massuel</name><affiliation wicri:level="3"><nlm:affiliation>Sanofi-Aventis, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Sanofi-Aventis, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Merhand, S" sort="Merhand, S" uniqKey="Merhand S" first="S" last="Merhand">S. Merhand</name><affiliation wicri:level="3"><nlm:affiliation>Association Française de l'Eczéma, Redon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Association Française de l'Eczéma, Redon</wicri:regionArea><placeName><region type="region">Région Bretagne</region><region type="old region">Région Bretagne</region><settlement type="city">Redon</settlement></placeName></affiliation></author><author><name sortKey="Mizutani, H" sort="Mizutani, H" uniqKey="Mizutani H" first="H" last="Mizutani">H. Mizutani</name><affiliation wicri:level="1"><nlm:affiliation>Mie University, Graduate School of Medicine and Mie University Hospital Tsu, Mie, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Mie University, Graduate School of Medicine and Mie University Hospital Tsu, Mie</wicri:regionArea><wicri:noRegion>Mie</wicri:noRegion></affiliation></author><author><name sortKey="Murota, H" sort="Murota, H" uniqKey="Murota H" first="H" last="Murota">H. Murota</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology, Osaka University, Osaka, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Dermatology, Osaka University, Osaka</wicri:regionArea><wicri:noRegion>Osaka</wicri:noRegion></affiliation></author><author><name sortKey="Murrell, D F" sort="Murrell, D F" uniqKey="Murrell D" first="D F" last="Murrell">D F Murrell</name><affiliation wicri:level="3"><nlm:affiliation>Department of Dermatology, St George Hospital, Sydney, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Dermatology, St George Hospital, Sydney</wicri:regionArea><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region></placeName></affiliation></author><author><name sortKey="Nakahara, T" sort="Nakahara, T" uniqKey="Nakahara T" first="T" last="Nakahara">T. Nakahara</name><affiliation wicri:level="4"><nlm:affiliation>Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka</wicri:regionArea><orgName type="university">Université de Kyūshū</orgName><placeName><settlement type="city">Fukuoka</settlement><region type="province">Kyūshū</region><region type="prefecture">Préfecture de Fukuoka</region></placeName></affiliation></author><author><name sortKey="Nasr, I" sort="Nasr, I" uniqKey="Nasr I" first="I" last="Nasr">I. Nasr</name><affiliation><nlm:affiliation>Retired, no affiliation.</nlm:affiliation><wicri:noCountry code="subField">no affiliation</wicri:noCountry></affiliation></author><author><name sortKey="Nograles, K" sort="Nograles, K" uniqKey="Nograles K" first="K" last="Nograles">K. Nograles</name><affiliation wicri:level="2"><nlm:affiliation>Celgene Corporation, Greater New York City Area Pharmaceuticals, New York, NY, U.S.A.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Celgene Corporation, Greater New York City Area Pharmaceuticals, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Ohya, Y" sort="Ohya, Y" uniqKey="Ohya Y" first="Y" last="Ohya">Y. Ohya</name><affiliation wicri:level="3"><nlm:affiliation>Division of Allergy, Department of Medical Subspecialties, National Center for Child Health and Development, Tokyo, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Division of Allergy, Department of Medical Subspecialties, National Center for Child Health and Development, Tokyo</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region></placeName></affiliation></author><author><name sortKey="Osterloh, I" sort="Osterloh, I" uniqKey="Osterloh I" first="I" last="Osterloh">I. Osterloh</name><affiliation wicri:level="1"><nlm:affiliation>Ostermed Ltd., Kent, U.K.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Ostermed Ltd., Kent</wicri:regionArea><wicri:noRegion>Kent</wicri:noRegion></affiliation></author><author><name sortKey="Pander, J" sort="Pander, J" uniqKey="Pander J" first="J" last="Pander">J. Pander</name><affiliation wicri:level="3"><nlm:affiliation>Celgene BV, Utrecht, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Celgene BV, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation></author><author><name sortKey="Prinsen, C" sort="Prinsen, C" uniqKey="Prinsen C" first="C" last="Prinsen">C. Prinsen</name><affiliation wicri:level="3"><nlm:affiliation>Department of Epidemiology and Biostatistics, EMGO+ Institute for Health and Care Research, VU University Medical Centre, Amsterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Epidemiology and Biostatistics, EMGO+ Institute for Health and Care Research, VU University Medical Centre, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Purkins, L" sort="Purkins, L" uniqKey="Purkins L" first="L" last="Purkins">L. Purkins</name><affiliation wicri:level="1"><nlm:affiliation>Ziarco Pharma Ltd, Kent, U.K.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Ziarco Pharma Ltd, Kent</wicri:regionArea><wicri:noRegion>Kent</wicri:noRegion></affiliation></author><author><name sortKey="Ridd, M" sort="Ridd, M" uniqKey="Ridd M" first="M" last="Ridd">M. Ridd</name><affiliation wicri:level="1"><nlm:affiliation>School of Social & Community Medicine, University of Bristol, Bristol, U.K.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>School of Social & Community Medicine, University of Bristol, Bristol</wicri:regionArea><wicri:noRegion>Bristol</wicri:noRegion></affiliation></author><author><name sortKey="Sach, T" sort="Sach, T" uniqKey="Sach T" first="T" last="Sach">T. Sach</name><affiliation wicri:level="1"><nlm:affiliation>Health Economics Group, University of East Anglia, Norwich, U.K.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Health Economics Group, University of East Anglia, Norwich</wicri:regionArea><wicri:noRegion>Norwich</wicri:noRegion></affiliation></author><author><name sortKey="Schuttelaar, M L A" sort="Schuttelaar, M L A" uniqKey="Schuttelaar M" first="M-L A" last="Schuttelaar">M-L A. Schuttelaar</name><affiliation wicri:level="3"><nlm:affiliation>Department of Dermatology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Dermatology, University Medical Center Groningen, University of Groningen, Groningen</wicri:regionArea><placeName><settlement type="city">Groningue</settlement><region nuts="2" type="province">Groningue (province)</region></placeName></affiliation></author><author><name sortKey="Shindo, S" sort="Shindo, S" uniqKey="Shindo S" first="S" last="Shindo">S. Shindo</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology, Osaka University, Osaka, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Dermatology, Osaka University, Osaka</wicri:regionArea><wicri:noRegion>Osaka</wicri:noRegion></affiliation></author><author><name sortKey="Smirnova, J" sort="Smirnova, J" uniqKey="Smirnova J" first="J" last="Smirnova">J. Smirnova</name><affiliation wicri:level="1"><nlm:affiliation>Department of Public Health Sciences, Karlstad University, Karlstad, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Public Health Sciences, Karlstad University, Karlstad</wicri:regionArea><wicri:noRegion>Karlstad</wicri:noRegion></affiliation></author><author><name sortKey="Sulzer, A" sort="Sulzer, A" uniqKey="Sulzer A" first="A" last="Sulzer">A. Sulzer</name><affiliation wicri:level="3"><nlm:affiliation>Sanofi-Aventis, Montpellier, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Sanofi-Aventis, Montpellier</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Languedoc-Roussillon</region><settlement type="city">Montpellier</settlement></placeName></affiliation></author><author><name sortKey="Synn Ve Gjerde, E" sort="Synn Ve Gjerde, E" uniqKey="Synn Ve Gjerde E" first="E" last="Synn Ve Gjerde">E. Synn Ve Gjerde</name><affiliation wicri:level="3"><nlm:affiliation>Psoriasis and Eczema Association of Norway, Oslo, Norway.</nlm:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Psoriasis and Eczema Association of Norway, Oslo</wicri:regionArea><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation></author><author><name sortKey="Takaoka, R" sort="Takaoka, R" uniqKey="Takaoka R" first="R" last="Takaoka">R. Takaoka</name><affiliation wicri:level="3"><nlm:affiliation>Department of Dermatology, University of São Paulo Medical School, São Paulo, Brazil.</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Department of Dermatology, University of São Paulo Medical School, São Paulo</wicri:regionArea><placeName><settlement type="city">São Paulo</settlement><region type="state">État de São Paulo</region></placeName></affiliation></author><author><name sortKey="Vestby Talmo, H" sort="Vestby Talmo, H" uniqKey="Vestby Talmo H" first="H" last="Vestby Talmo">H. Vestby Talmo</name><affiliation wicri:level="3"><nlm:affiliation>Sanofi-Aventis, Montpellier, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Sanofi-Aventis, Montpellier</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Languedoc-Roussillon</region><settlement type="city">Montpellier</settlement></placeName></affiliation></author><author><name sortKey="Tauber, M" sort="Tauber, M" uniqKey="Tauber M" first="M" last="Tauber">M. Tauber</name><affiliation wicri:level="3"><nlm:affiliation>Toulouse University, Toulouse, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Toulouse University, Toulouse</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Midi-Pyrénées</region><settlement type="city">Toulouse</settlement></placeName></affiliation></author><author><name sortKey="Torchet, F" sort="Torchet, F" uniqKey="Torchet F" first="F" last="Torchet">F. Torchet</name><affiliation wicri:level="1"><nlm:affiliation>Mie University, Graduate School of Medicine and Mie University Hospital Tsu, Mie, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Mie University, Graduate School of Medicine and Mie University Hospital Tsu, Mie</wicri:regionArea><wicri:noRegion>Mie</wicri:noRegion></affiliation></author><author><name sortKey="Volke, A" sort="Volke, A" uniqKey="Volke A" first="A" last="Volke">A. Volke</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology, University of Tartu, Tartu, Estonia.</nlm:affiliation><country xml:lang="fr">Estonie</country><wicri:regionArea>Department of Dermatology, University of Tartu, Tartu</wicri:regionArea><wicri:noRegion>Tartu</wicri:noRegion></affiliation></author><author><name sortKey="Wahlgren, C F" sort="Wahlgren, C F" uniqKey="Wahlgren C" first="C-F" last="Wahlgren">C-F Wahlgren</name><affiliation wicri:level="1"><nlm:affiliation>Dermatology Unit, Department of Medicine, Karolinska Institutet, Solna, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Dermatology Unit, Department of Medicine, Karolinska Institutet, Solna</wicri:regionArea><wicri:noRegion>Solna</wicri:noRegion></affiliation></author><author><name sortKey="Weidinger, S" sort="Weidinger, S" uniqKey="Weidinger S" first="S" last="Weidinger">S. Weidinger</name><affiliation wicri:level="3"><nlm:affiliation>Department of Dermatology, Venereology and Allergy University Hospital Schleswig-Holstein, Kiel, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Dermatology, Venereology and Allergy University Hospital Schleswig-Holstein, Kiel</wicri:regionArea><placeName><region type="land" nuts="2">Schleswig-Holstein</region><settlement type="city">Kiel</settlement></placeName></affiliation></author><author><name sortKey="Weisshaar, E" sort="Weisshaar, E" uniqKey="Weisshaar E" first="E" last="Weisshaar">E. Weisshaar</name><affiliation wicri:level="3"><nlm:affiliation>Occupational and Environmental Dermatology, Department of Social Medicine, University of Heidelberg, Heidelberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Occupational and Environmental Dermatology, Department of Social Medicine, University of Heidelberg, Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Wollenberg, A" sort="Wollenberg, A" uniqKey="Wollenberg A" first="A" last="Wollenberg">A. Wollenberg</name><affiliation wicri:level="3"><nlm:affiliation>Department of Dermatology and Allergy, Ludwig-Maximilian University, Munich, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Dermatology and Allergy, Ludwig-Maximilian University, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName></affiliation></author><author><name sortKey="Yamaga, K" sort="Yamaga, K" uniqKey="Yamaga K" first="K" last="Yamaga">K. Yamaga</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology, Osaka University, Osaka, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Dermatology, Osaka University, Osaka</wicri:regionArea><wicri:noRegion>Osaka</wicri:noRegion></affiliation></author><author><name sortKey="Zhao, C Y" sort="Zhao, C Y" uniqKey="Zhao C" first="C Y" last="Zhao">C Y Zhao</name><affiliation wicri:level="3"><nlm:affiliation>Department of Dermatology, St George Hospital, Sydney, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Dermatology, St George Hospital, Sydney</wicri:regionArea><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region></placeName></affiliation></author><author><name sortKey="Spuls, P I" sort="Spuls, P I" uniqKey="Spuls P" first="P I" last="Spuls">P I Spuls</name><affiliation wicri:level="4"><nlm:affiliation>Department of Dermatology, Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Dermatology, Academic Medical Centre, University of Amsterdam, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region><settlement type="city">Amsterdam</settlement></placeName><orgName type="university">Université d'Amsterdam</orgName></affiliation></author></analytic><series><title level="j">The British journal of dermatology</title><idno type="eISSN">1365-2133</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Checklist</term><term>Clinical Trials as Topic</term><term>Dermatitis, Atopic (therapy)</term><term>Dermatologic Agents (therapeutic use)</term><term>Global Health</term><term>Humans</term><term>Long-Term Care</term><term>Patient Reported Outcome Measures</term><term>Quality of Life</term><term>Review Literature as Topic</term><term>Treatment Outcome</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Eczéma atopique ()</term><term>Essais cliniques comme sujet</term><term>Humains</term><term>Liste de contrôle</term><term>Littérature de revue comme sujet</term><term>Mesures des résultats rapportés par les patients</term><term>Produits dermatologiques (usage thérapeutique)</term><term>Qualité de vie</term><term>Résultat thérapeutique</term><term>Santé mondiale</term><term>Soins de longue durée</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Dermatologic Agents</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Dermatitis, Atopic</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Produits dermatologiques</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Checklist</term><term>Clinical Trials as Topic</term><term>Global Health</term><term>Humans</term><term>Long-Term Care</term><term>Patient Reported Outcome Measures</term><term>Quality of Life</term><term>Review Literature as Topic</term><term>Treatment Outcome</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Eczéma atopique</term><term>Essais cliniques comme sujet</term><term>Humains</term><term>Liste de contrôle</term><term>Littérature de revue comme sujet</term><term>Mesures des résultats rapportés par les patients</term><term>Qualité de vie</term><term>Résultat thérapeutique</term><term>Santé mondiale</term><term>Soins de longue durée</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">This article is a report of the fourth meeting of the Harmonising Outcome Measures for Eczema (HOME) initiative held in Malmö, Sweden on 23-24 April 2015 (HOME IV). The aim of the meeting was to achieve consensus over the preferred outcome instruments for measuring patient-reported symptoms and quality of life for the HOME core outcome set for atopic eczema (AE). Following presentations, which included data from systematic reviews, consensus discussions were held in a mixture of whole group and small group discussions. Small groups were allocated a priori to ensure representation of different stakeholders and countries. Decisions were voted on using electronic keypads. For the patient-reported symptoms, the group agreed by vote that itch, sleep loss, dryness, redness/inflamed skin and irritated skin were all considered essential aspects of AE symptoms. Many instruments for capturing patient-reported symptoms were discussed [including the Patient-Oriented SCOring Atopic Dermatitis index, Patient-Oriented Eczema Measure (POEM), Self-Administered Eczema Area and Severity Index, Itch Severity Scale, Atopic Dermatitis Quickscore and the Nottingham Eczema Severity Score] and, by consensus, POEM was selected as the preferred instrument to measure patient-reported symptoms. Further work is needed to determine the reliability and measurement error of POEM. Further work is also required to establish the importance of pain/soreness and the importance of collecting information regarding the intensity of symptoms in addition to their frequency. Much of the discussion on quality of life concerned the Dermatology Life Quality Index and Quality of Life Index for Atopic Dermatitis; however, consensus on a preferred instrument for measuring this domain could not be reached. In summary, POEM is recommended as the HOME core outcome instrument for measuring AE symptoms.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>Brésil</li><li>Canada</li><li>Danemark</li><li>Estonie</li><li>France</li><li>Japon</li><li>Norvège</li><li>Pays-Bas</li><li>Royaume-Uni</li><li>Suède</li><li>États-Unis</li></country><region><li>Alabama</li><li>Angleterre</li><li>Bade-Wurtemberg</li><li>Bavière</li><li>Californie</li><li>District de Dresde</li><li>District de Haute-Bavière</li><li>District de Karlsruhe</li><li>Grand Londres</li><li>Groningue (province)</li><li>Hollande-Septentrionale</li><li>Hovedstaden</li><li>Kyūshū</li><li>Languedoc-Roussillon</li><li>Midi-Pyrénées</li><li>Nottinghamshire</li><li>Nouvelle-Galles du Sud</li><li>Occitanie (région administrative)</li><li>Oregon</li><li>Pays de la Loire</li><li>Préfecture de Fukuoka</li><li>Région Bretagne</li><li>Région de Kantō</li><li>Saxe (Land)</li><li>Schleswig-Holstein</li><li>Utrecht (province)</li><li>État de New York</li><li>État de São Paulo</li><li>Île-de-France</li><li>Østlandet</li></region><settlement><li>Amsterdam</li><li>Copenhague</li><li>Dresde</li><li>Fukuoka</li><li>Groningue</li><li>Heidelberg</li><li>Kiel</li><li>Londres</li><li>Montpellier</li><li>Munich</li><li>Nantes</li><li>Nottingham</li><li>Oslo</li><li>Paris</li><li>Redon</li><li>Sydney</li><li>São Paulo</li><li>Tokyo</li><li>Toulouse</li><li>Utrecht</li></settlement><orgName><li>Université d'Amsterdam</li><li>Université de Kyūshū</li><li>Université de Nottingham</li></orgName></list><tree><noCountry><name sortKey="Burton, T" sort="Burton, T" uniqKey="Burton T" first="T" last="Burton">T. Burton</name><name sortKey="Marquort, B" sort="Marquort, B" uniqKey="Marquort B" first="B" last="Marquort">B. Marquort</name><name sortKey="Nasr, I" sort="Nasr, I" uniqKey="Nasr I" first="I" last="Nasr">I. Nasr</name></noCountry><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Chalmers, J R" sort="Chalmers, J R" uniqKey="Chalmers J" first="J R" last="Chalmers">J R Chalmers</name></region><name sortKey="Bragg, A" sort="Bragg, A" uniqKey="Bragg A" first="A" last="Bragg">A. Bragg</name><name sortKey="Flohr, C" sort="Flohr, C" uniqKey="Flohr C" first="C" last="Flohr">C. Flohr</name><name sortKey="Graff, A L B" sort="Graff, A L B" uniqKey="Graff A" first="A L B" last="Graff">A L B. Graff</name><name sortKey="Humphreys, R" sort="Humphreys, R" uniqKey="Humphreys R" first="R" last="Humphreys">R. Humphreys</name><name sortKey="Osterloh, I" sort="Osterloh, I" uniqKey="Osterloh I" first="I" last="Osterloh">I. Osterloh</name><name sortKey="Purkins, L" sort="Purkins, L" uniqKey="Purkins L" first="L" last="Purkins">L. Purkins</name><name sortKey="Ridd, M" sort="Ridd, M" uniqKey="Ridd M" first="M" last="Ridd">M. Ridd</name><name sortKey="Sach, T" sort="Sach, T" uniqKey="Sach T" first="T" last="Sach">T. Sach</name><name sortKey="Thomas, K S" sort="Thomas, K S" uniqKey="Thomas K" first="K S" last="Thomas">K S Thomas</name><name sortKey="Williams, H C" sort="Williams, H C" uniqKey="Williams H" first="H C" last="Williams">H C Williams</name></country><country name="États-Unis"><region name="Oregon"><name sortKey="Simpson, E" sort="Simpson, E" uniqKey="Simpson E" first="E" last="Simpson">E. Simpson</name></region><name sortKey="Abuabara, K" sort="Abuabara, K" uniqKey="Abuabara K" first="K" last="Abuabara">K. Abuabara</name><name sortKey="Ardeleanu, M" sort="Ardeleanu, M" uniqKey="Ardeleanu M" first="M" last="Ardeleanu">M. 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Yamaga</name></country><country name="Australie"><region name="Nouvelle-Galles du Sud"><name sortKey="Murrell, D F" sort="Murrell, D F" uniqKey="Murrell D" first="D F" last="Murrell">D F Murrell</name></region><name sortKey="Zhao, C Y" sort="Zhao, C Y" uniqKey="Zhao C" first="C Y" last="Zhao">C Y Zhao</name></country><country name="Estonie"><noRegion><name sortKey="Volke, A" sort="Volke, A" uniqKey="Volke A" first="A" last="Volke">A. Volke</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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